Changes in the Number of Polymorphonuclear Leukocytes and Concentrations of IL-8 and Granulocyte Elastase in the Vaginas of Normal Pregnant Women
| Autor: | Ikuo Sato, Hisanori Minakami, Toshio Aoya, Shigeki Matsubara, Tetsuo Yamada, Yasuhiro Kohmura |
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| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Pregnancy medicine.medical_treatment Immunology Elastase Obstetrics and Gynecology Ripening Biology Granulocyte medicine.disease Andrology Endocrinology medicine.anatomical_structure Cytokine Reproductive Medicine Internal medicine medicine Vagina Immunology and Allergy Gestation Interleukin 8 |
| Zdroj: | American Journal of Reproductive Immunology. 47:98-103 |
| ISSN: | 1046-7408 |
| DOI: | 10.1034/j.1600-0897.2002.1o012.x |
| Popis: | PROBLEM: It is unknown whether the number of vaginal polymorphonuclear leukocytes (vPMNs) of healthy pregnant women changes during pregnancy. METHOD OF STUDY: We studied 23 women after 14.7 ± 3.6 weeks, 37 women after 25.2 ± 3.1 weeks, and 26 women after 32.9 ± 2.0 weeks of gestation. Numbers of total vPMNs, viable vPMNs, dead vPMNs, percentage viability of vPMNs, and concentrations of IL-8 and elastase activity were determined in vaginal washings. RESULTS: The vPMNs, including viable and dead vPMNs, significantly increased with advancing gestation from 9.9 ± 8.6 × 105 to 13.1 ± 13.4 × 105, and to 27.1 ± 26.6 × 105 (r=0.315, P |
| Databáze: | OpenAIRE |
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