Synthesis of 3'-Amino-3'-deoxyadenosine Derivatives as Potential Drugs for the Treatment of Malaria

Autor:	Piet Herdewijn, E Vandeneeckhout, G Francois, J Soenens
Rok vydání:	1995
Předmět:	biology Chemistry Plasmodium falciparum General Medicine medicine.disease biology.organism_classification Biochemistry Virology In vitro parasitic diseases Genetics medicine Molecular Medicine Parasite hosting Deoxyadenosine Derivatives Nucleoside Malaria
Zdroj:	Nucleosides, Nucleotides and Nucleic Acids. 14:409-411
ISSN:	1525-7770
DOI:	10.1080/15257779508012396
Popis:	A series of 3′-substituted 3′-amino-3′-deoxyadenosine analogues were synthesized and subsequently tested against the human malaria parasite Plasmodium falciparum in vitro. Several amongst them displayed pronounced antiplasmodial activities.
Databáze:	OpenAIRE
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