| Popis: |
SLSEPs are useful in evaluation of post anoxic comatose patients (PAC), and are a negative, but not positive, prognostic factor for awake. N60 is a component of MLSPEs, evoked by painful simultaneously stimulation of bilateral median nerve. Literature data suggests that MLSEPs could have a positive prognostic value for awake in post anoxic comatose patients, but latency normative data are not available. Aim of the study is to set the MLSEPs recording method in ICU, to determine normative data, and to apply it for evaluation of PAC patients with no negative prognosis factors for awake (bilateral N20 absence, no EEG activity). The better recording method was defined as follows: referential derivation, stimulation parameters: 0.2 ms, 3.3 Hz, 42 mA for healthy subjects and 50 mA for comatose patients. N60 peak latency normative data were collected from 21 healthy subjects. MLSEPs were applied to PAC patients. Nine patients have been enrolled, of these three patients underwent to MLSEPs study (Six patients did not match inclusion criteria). Latencies normative data are reported. MLSEPs were detected in 2 of the three studied patients. They awaked. In the third patient MLSEPs were absent and did never awake. Our data seems to confirm that early presence of MLSEPs in PAC patients may be a prognostic positive marker for awake. |
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