Antimicrobial activity of the leaf extract and fractions of Lupinus arboreus
| Autor: | I. Nnatuanya, L U Amazu, C E Okolo, S C Ohadoma |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Pharmacology
Chromatography biology Ethyl acetate Pharmaceutical Science Plant Science Antimicrobial biology.organism_classification chemistry.chemical_compound Complementary and alternative medicine chemistry Lupinus arboreus Antimicrobial effect Drug Discovery Maceration (wine) Methanol Candida albicans |
| Zdroj: | Journal of Medicinal Plants Research. 8:386-391 |
| ISSN: | 1996-0875 |
| Popis: | The antimicrobial effect of the leaf extract and fractions of Lupinus arboreus was investigated. The crude methanol extract (CME) of the dried leaves obtained by 48 h cold maceration was fractionated into n-hexane fraction (HEF), ethyl acetate fraction (EAF), and methanol fraction (MEF); and evaluated using modified agar-well diffusion method. The results showed that the extract and fractions at varying concentrations, exerted strong antimicrobial activity on some of the test organisms. However, a weak activity was observed on the tested fungi-Aspergillus niger and Candida albicans. Ethyl acetate fraction showed the highest activity on many organisms than extract and other fractions. Key words: Lupinus arboreus, antimicrobial activity, standard drugs, test organisms, extracts and fractions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|