Dietary Effects of Porphyran from Porphyra yezoensis on Growth and Lipid Metabolism of Sprague-Dawley Rats
| Autor: | Hirofumi Tachibana, Toshihisa Sumi, Keisuke Tsuge, Takashi Yoshimura, Koji Yamada, Masaaki Okabe |
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| Rok vydání: | 2004 |
| Předmět: |
Marketing
chemistry.chemical_classification Cholesterol General Chemical Engineering Porphyran Fatty acid Adipose tissue Lipid metabolism Biology Industrial and Manufacturing Engineering chemistry.chemical_compound Sulfation chemistry Biochemistry Ingestion Food science Sugar Food Science Biotechnology |
| Zdroj: | Food Science and Technology Research. 10:147-151 |
| ISSN: | 1881-3984 1344-6606 |
| DOI: | 10.3136/fstr.10.147 |
| Popis: | Effects of porphyran (POR), a sulfated galactan from an edible red alga Porphyra yezoensis (Susabinori), on growth and lipid metabolism were examined using Sprague-Dawley rats fed a cholesterol-free diet. Rats were divided into four dietary groups: those fed diets containing 5% cellulose (control), agar or two types of POR differing in sugar composition and sulfate content (low sulfate content, LS-POR and high sulfate content, HS-POR) for 3 weeks. Ingestion of the diets containing LS- and HS-POR resulted in a significant decrease in food intake and body weight gain relative to the control diet. Renal adipose tissue weight and serum cholesterol level were also significantly lower in the LS-POR group and the HS-POR group than in the other groups. In contrast, agar, which consists of the same sugar components as POR, had no effect on the above-mentioned growth and lipid parameters. Fecal excretion of neutral sterols was markedly enhanced by POR ingestion, suggesting that POR has a potent effect to interfere with the absorption of neutral sterols within the gastrointestinal tract. Fecal excretion of fatty acids and neutral sterols was significantly higher in the LS-POR group than in the HS-POR group, and it was suggested that the ability to interfere with the absorption of cholesterol and fatty acid within the gastrointesitinal tract depends on the sulfation rate of porphyan. |
| Databáze: | OpenAIRE |
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