Fine Structural Characterization of the Main Immunogenic Region of the Nicotinic Acetylcholine Receptor

Autor: Manh-Thong Cung, Michel Marraud, I. Papadouli, S. Potamianos, V. Tsikaris, H. Bairaktari, I. Hadjidakis, C. Sakarellos, Socrates J. Tzartos
Rok vydání: 1989
Předmět:
Zdroj: Molecular Biology of Neuroreceptors and Ion Channels ISBN: 9783642741579
DOI: 10.1007/978-3-642-74155-5_31
Popis: The nicotinic acetylcholine receptor (AChR) of fish electric organs and mammalian muscle is a complex transmembrane glycoprotein formed by five homologous subunits in a stoichiometry α2βγδ, of mol. weight 290.000. The two α-subunits carry the two ACh binding sites. The complete amino acid sequence of Torpedo electric organ and mammalian muscle AChR subunits is known (reviewed in Numa et al., 1983; Changeux & Revan, 1987).
Databáze: OpenAIRE