Formation of new C–O and C–N bonds via base promoted Csp2–Csp3 bond cleavage of α-nitro ketone

Autor:	Arun Jyoti Borah, Prodeep Phukan, Manas Jyoti Sarma, Kamal Krishna Rajbongshi
Rok vydání:	2015
Předmět:	chemistry.chemical_classification Ketone Base (chemistry) Organic Chemistry Biochemistry Medicinal chemistry Catalysis Potassium carbonate chemistry.chemical_compound chemistry Nucleophile Amide Drug Discovery Nitro Organic chemistry Bond cleavage
Zdroj:	Tetrahedron Letters. 56:7008-7011
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2015.11.002
Popis:	A catalyst free protocol has been developed for nucleophilic C sp 2 – C sp 3 bond cleavage of α-nitroketone in the presence of potassium carbonate to create new C–O and C–N bonds. A series of different substituted α-nitroketones could be selectively cleaved and converted into corresponding esters and tosylamides in the presence of alcohols and bromamine-T, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d5b5c5d0641380b47642eb17d8287836 https://doi.org/10.1016/j.tetlet.2015.11.002 Zobrazit plný text záznamu Full Text from ScienceDirect