| Popis: |
Dermatofibrosarcoma protuberans (DFSP) is best described as a fibroblastic neoplasm. It is a low to moderate grade type of soft tissue sarcoma (STS) arising from cells of mesenchymal origin in the dermal layer of the skin1-4. This entity was first described in 1924 by Darier and Ferrand5. Though DFSP is a low grade malignancy, fibrosarcomatous variant can be very aggressive especially when provoked by inadequate excision. It is a rare type of skin cancer that can grow deeply into the skin to invade the fat, muscle, and bone. DFSP is a locally aggressive tumour and rarely metastasizes. This gives it a higher survival rate when adequately excised1-7. In developing countries however, late presentation to hospitals are very common. Patients here seek help first from unqualified persons and only come to the specialists late into their illness. This has led to poor outcomes in many cases. |
