Comparison of Volatile Sulfur Compound Concentrations Measured with a Sulfide Detector vs. Gas Chromatography
| Autor: | J. Furne, G. Majerus, P. Lenton, J. Springfield, D.G. Levitt, M.D. Levitt |
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| Rok vydání: | 2002 |
| Předmět: | |
| Zdroj: | Journal of Dental Research. 81:140-143 |
| ISSN: | 1544-0591 0022-0345 |
| Popis: | The accuracy of the Halimeter®, an inexpensive, simple instrument that measures total breath volatile sulfur compounds (VSCs), has not been adequately tested. We compared Halimeter® measurements with those obtained with a specific and sensitive gas chromatographic (GC) technique. The Halimeter® gave different, bi-exponential responses to a constant concentration of different VSCs: The relative response rate and sensitivity were hydrogen sulfide > methyl mercaptan > dimethylsulfide. The transient peak VSC concentration of oral samples was reached long before the sulfide detector fully responded. The GC measurement of initial total VSCs in breath samples was 2.7 ± 0.48 times greater than the peak concentration of the Halimeter®. However, the plateau phase measurement of the Halimeter® was 25% greater than that of GC. While GC and Halimeter® measurements positively correlated, appreciable differences were observed. In studies where relatively precise VSC measurements are required, GC is the preferable technique. |
| Databáze: | OpenAIRE |
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