The long-term effect of surgical aortic valve replacement on arterial stiffness and wave reflections

Autor:	E Sigala, D Terentes-Printzios, G N Baikoussis, A Katsaros, N Koumallos, V Lozos, N Giakis, K Filis, K Tsioufis, C Vlachopoulos
Rok vydání:	2022
Předmět:	Cardiology and Cardiovascular Medicine
Zdroj:	European Heart Journal. 43
ISSN:	1522-9645 0195-668X
DOI:	10.1093/eurheartj/ehac544.1603
Popis:	Background Assessing arterial properties in patients with aortic valve stenosis undergoing surgical aortic valve replacement (SAVR) is difficult, and the results to date have been inconclusive. Purpose We sought to investigate how SAVR affects vascular stiffness in the short and long term. Methods We included 69 patients (mean age 70.8±8.4 years, 62% men) with severe symptomatic aortic stenosis who underwent SAVR. Arterial stiffness was assessed using the carotid femoral pulse wave velocity (cfPWV) and brachial-ankle pulse wave velocity (baPWV). Measurements in patients with an ankle-brachial index (ABI) Results Immediately after SAVR there was an increase in cfPWV (8.04±1.3 m/s vs 8.54±1.6 m/s, p=0.02) that was sustained at 1 year (8.04±1.3 m/s vs 9.42±2.4 m/s, p≤0.001). Similarly, baPWV (n=55) increased in the acute phase (1633±429 cm/s vs 2014±606 cm/s, p Conclusions After SAVR the arterial system shows an increase of stiffness in response to the acute relief of the obstruction, which is retained in the long term. Funding Acknowledgement Type of funding sources: None.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d58abc8e56e0b8adada8d06002ba0622 https://doi.org/10.1093/eurheartj/ehac544.1603 Zobrazit plný text záznamu