Borylative Cyclization of 1,6-Allenynes Driven by BCl3

Autor:	Zhantao Yang, Chun-Hua Yang, Mingzhu Liu, Xiangkun Sun, Congcong Niu, Fangjie Zheng, Zhiwei Zhang, Ling Jiang, Xiangtao Kong
Rok vydání:	2021
Předmět:	Steric effects chemistry.chemical_compound Chemistry Stereochemistry Intramolecular force Allene Organic Chemistry Physical and Theoretical Chemistry Biochemistry
Zdroj:	Organic Letters. 23:8050-8055
ISSN:	1523-7052 1523-7060
DOI:	10.1021/acs.orglett.1c03062
Popis:	A metal-free intramolecular borylative cyclization of 1,6-allenynes driven by BCl3 was developed. This method provides a general and practical strategy to construct valuable pyrrolidines containing all-carbon quaternary centers or 3,5-dihydroazepine derivatives depending on the substituents of the allene, with conjugative and sterically hindered phenyl groups favoring the latter.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d58576b42f5698d057622a14fc02aaaf https://doi.org/10.1021/acs.orglett.1c03062 Zobrazit plný text záznamu