Synthesis of Ferrocene-Fused Pyrans through Alkynoxy-Directed C–H Activation/Cyclization

Autor:	Yuichiro Tokoro, Takashi Mitsui, Shin-ichi Fukuzawa, Ryosuke Haraguchi, Kengo Sugita, Tamejiro Hiyama, Masato Harada, Yasunori Minami
Rok vydání:	2018
Předmět:	010405 organic chemistry Enantioselective synthesis chemistry.chemical_element General Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry 0104 chemical sciences Catalysis chemistry.chemical_compound Ferrocene chemistry Pyran Palladium
Zdroj:	Bulletin of the Chemical Society of Japan. 91:839-845
ISSN:	1348-0634 0009-2673
DOI:	10.1246/bcsj.20170415
Popis:	We have developed palladium-catalyzed C–H activation and cyclization of alkynyl ferrocenyl ethers with various alkynes, providing ferrocene-fused pyran derivatives. As a preliminary result, we also achieved the asymmetric version of this reaction with high enantioselectivity, providing the first example of the catalytic asymmetric synthesis of an enantio-enriched ferrocene-fused oxacycle.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d56b960921a3ecacc5640a799952b217 https://doi.org/10.1246/bcsj.20170415 Zobrazit plný text záznamu