Effect of subchronic administration of phenazepam and synthetic antioxidants on cerebral cortical synaptic membrane function of rats exposed to long-term stress
| Autor: | K. M. Dyumaev, L. D. Smirnov, Eremenko Av, E. M. Gankina, A. V. Val'dman, Avdulov Na |
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| Rok vydání: | 1988 |
| Předmět: |
Drug
CATS Chemistry media_common.quotation_subject Phenazepam General Medicine Pharmacology General Biochemistry Genetics and Molecular Biology Coronary circulation medicine.anatomical_structure Cerebral cortex Synaptic membrane Long term stress medicine Neuroscience Function (biology) medicine.drug media_common |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 105:46-49 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | In the experiments on different animal species (mice, cats, dogs) lithium hydroxybutyrate has been shown to have antihypoxic and anti-ischemic effects. Lithium hydroxybutyrate improved the functional state of the ischemic myocardium, stimulated the accumulation of macroergic phosphates (ATP) in the heart, protected the ischemic myocardium and delayed the progression of the reversible ischemic damage into the irreversible one. The improvement of the collateral coronary circulation plays an important role in the anti-ischemic action of the drug. |
| Databáze: | OpenAIRE |
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