Proliferation characteristics of cultured human aortic endothelial cells and expression of adhesion molecules

Autor:	O. P. Il'inskaya, S. A. Loktionova, I. V. Balyasnikova
Rok vydání:	1996
Předmět:	education.field_of_study Cell adhesion molecule Chemistry Population Soluble cell adhesion molecules General Medicine Adhesion General Biochemistry Genetics and Molecular Biology Umbilical vein Cell biology Neural cell adhesion molecule Cell adhesion education Lymphocyte homing receptor
Zdroj:	Bulletin of Experimental Biology and Medicine. 122:842-845
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf02445165
Popis:	Basal expression of the adhesion molecules P-selectin and ICAM-1, which mediate adhesion and transendothelial migration of leukocytes, by endothelial cells of human aorta and umbilical vein and its relationship with the proliferative behavior of these cells are studied in primary prolonged cultures. Inverse proportionality between the percentage of resting endothelial cells and those expressing the adhesion molecules in preconfluent and confluent monolayers, on the one hand, and the percentage of cells in the active cycle which do not express the adhesion molecules, on the other, is demonstrated. This relationship is one of the major causes of thein vitro functional heterogeneity of the endotheliocyte population in the expression of adhesion molecules and its adhesiveness for leukocytes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d51df4cfe2945fa97644435641e8f769 https://doi.org/10.1007/bf02445165 Zobrazit plný text záznamu Full text from SpringerLink