In Vivo Metabolism of Aristolochic Acid I and II in Rats Is Influenced by Their Coexposure

Autor:	Václav Martínek, František Bárta, Volker M. Arlt, Petr Hodek, Kevin Kotalík, Marie Stiborová, Alena Dedı́ková, Šárka Dušková, Jaroslav Mráz
Rok vydání:	2020
Předmět:	Balkan endemic nephropathy chemistry.chemical_compound chemistry medicine Aristolochic acid In vivo metabolism Aristolochic acid nephropathy General Medicine Pharmacology Aristolochic acid I Toxicology medicine.disease
Zdroj:	Chemical Research in Toxicology. 33:2804-2818
ISSN:	1520-5010 0893-228X
DOI:	10.1021/acs.chemrestox.0c00198
Popis:	The plant extract aristolochic acid (AA), containing aristolochic acid I (AAI) and II (AAII) as major components, causes aristolochic acid nephropathy and Balkan endemic nephropathy, unique renal d...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d4fcfd17751f58285c1aa40c80804a8f https://doi.org/10.1021/acs.chemrestox.0c00198 Zobrazit plný text záznamu