BCR/ABL1-positive B-lymphoblastic Lymphoma Successfully Treated with Dasatinib-combined Chemotherapy
| Autor: | Madoka Kanda-Kato, Chika Yamada, Kimimori Kamijyo, Yoshimitsu Shimomura, Satoshi Yoshioka, Takayuki Ishikawa, Daisuke Yamashita |
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| Rok vydání: | 2021 |
| Předmět: |
B Lymphoblastic Lymphoma
medicine.medical_specialty business.industry Combination chemotherapy Consolidation Chemotherapy General Medicine Gastroenterology Dasatinib Transplantation medicine.anatomical_structure hemic and lymphatic diseases Internal medicine Internal Medicine medicine Duodenum Prednisolone Bone marrow business medicine.drug |
| Zdroj: | Internal Medicine. 60:3149-3153 |
| ISSN: | 1349-7235 0918-2918 |
| Popis: | We herein report a rare case of BCR-ABL1-positive B-lymphoblastic lymphoma (B-LBL). An 18-year-old woman had a history of persistent left-sided chest pain. Positron emission tomography showed increased metabolic activity in the fifth rib, duodenum, and pancreas. The pathological findings of the pancreas, duodenum, and bone marrow confirmed the diagnosis of B-LBL. Polymerase chain reaction of duodenum and bone marrow also revealed a minor BCR-ABL1 fusion gene. She was diagnosed with BCR-ABL1-positive B-LBL and administered dasatinib and prednisolone. She achieved complete remission two weeks after the initiation of the treatment. She received stem cell transplantation after consolidation chemotherapy and sustained complete remission. |
| Databáze: | OpenAIRE |
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