Prognostic role of oral atropine in the subacute phase of organophosphate poisoning

Autor:	Rahul Chauhan, Sanjay Sharma, K. N. Venkateshwara Prasad, Pradeep Kumar Vegi, CD Dayanand
Rok vydání:	2013
Předmět:	business.industry Pharmacology medicine.disease Acetylcholinesterase Organophosphate poisoning Atropine chemistry.chemical_compound chemistry Dichlorvos Toxicity medicine Cholinergic Ingestion business Acetylcholine medicine.drug
Zdroj:	Nigerian Journal of Experimental and Clinical Biosciences. 1:53
ISSN:	2348-0149
DOI:	10.4103/2348-0149.123966
Popis:	Organophosphates (OPs) are widely used as insecticides. Accidental OP poisoning is reported world over. These compounds inhibit the enzyme acetylcholinesterase within the peripheral and central nervous system by phosphorylation of its esteratic site. The resultant accumulation of acetylcholine at the cholinergic receptor sites, leads to signs of cholinergic toxicity. Accidental OP ingestion has rarely been reported in young toddlers. We report a case of acute OP poisoning (dichlorvos) in an 18-month-old boy with special reference to use of oral atropine treatment in subacute phase.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d4f4a2223bfe34ec7f453bdcdab9f0a5 https://doi.org/10.4103/2348-0149.123966 Zobrazit plný text záznamu