An NBD–NH2 fluorescent probe for bioimaging: existence of a specific detection of ClO−

Autor:	Mengsheng Xu, Jianhong Wang, Jipeng Chen, Di Zhang, Yunxia Yang, Le Wang
Rok vydání:	2018
Předmět:	Detection limit HEPES chemistry.chemical_compound 010405 organic chemistry Chemistry Specific detection High selectivity General Chemistry 010402 general chemistry Photochemistry 01 natural sciences Fluorescence 0104 chemical sciences
Zdroj:	Monatshefte für Chemie - Chemical Monthly. 149:1003-1008
ISSN:	1434-4475 0026-9247
DOI:	10.1007/s00706-018-2143-9
Popis:	A fluorescent probe 4-amino-7-nitrobenz-2-oxa-1,3-diazole NBD–NH2 for critical sensing hypochlorous (ClO−) has been developed in this paper. Probe NBD–NH2 exhibited excellent sensitivity and high selectivity toward detection of ClO− in CH3CH2OH/HEPES solution (1:4, v/v, 10 mM, pH 7.4), where the detection limit as low as 40 nM. The green fluorescence of NBD–NH2 was distinctly quenched by addition of ClO−. In addition, the new probe was also applied for bioimaging using HeLa cells and exist a critical detection of ClO− in living cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d4ee890f785d200f1f325e95b81a3745 https://doi.org/10.1007/s00706-018-2143-9 Zobrazit plný text záznamu Full text from SpringerLink