| Popis: |
Osteoporosis results in the thinning of the cortical shell and trabecular struts of the bones such that the loads of normal daily activities can result in fractures.In the case of osteoporosis of the vertebrae, vertebral compression fractures (VCF) can occur spontaneously or as the result of a low-energy trauma, resulting in chronic pain and reduced mobility [1]. If left untreated, multiple VCFs can result in chronic pain, loss of height, and spinal deformity.More importantly, VCF incidence has been increasing with the associated aging of the demographic.Furthermore, there are approximately 440,000 VCFs per year in Europe, resulting in a direct annual cost of $440 MM, and 700,000 VCFs per year in the United States, resulting in a direct annual cost of $750 MM [2–5]. |
