Methyl Gallate as an Antioxidant and Anti-HIV Agent

Autor: Ryan Tse, Helen Chan, Fang Liu, Charlene C.W. Ng, Tzi Bun Ng, Tak Fu Tse, John Wong, Chi F. Cheung, Chit Tam
Rok vydání: 2018
Předmět:
Popis: Methyl gallate is an antioxidant found in a great variety of plant species including some edible beans and also mushrooms. It protects a diversity of cells including liver cells, kidney cells, heart cells, neuronal cells, and fat cells from oxidative stress induced by chemicals such as hydrogen peroxide. It upregulates antioxidant enzymes. It inhibits three key enzymes crucial to the HIV life cycle including reverse transcriptase, protease, and integrase. Methyl gallate inhibits HIV-1 replication in pseudovirus-infected TZM-BL cells.
Databáze: OpenAIRE