Solid-phase Suzuki cross-coupling reactions using a phosphine ligand based on a phospha-adamantane framework

Autor:	Konrad Bleicher, Tim Brenstrum, James McNulty, Stephan A. Ohnmacht, Alfredo Capretta
Rok vydání:	2004
Předmět:	Ligand Aryl Adamantane Organic Chemistry chemistry.chemical_element Biochemistry Combinatorial chemistry Coupling reaction Catalysis chemistry.chemical_compound chemistry Suzuki reaction Drug Discovery Polymer chemistry Phosphine Palladium
Zdroj:	Tetrahedron Letters. 45:5661-5663
ISSN:	0040-4039
Popis:	The use of a catalyst system based on Pd 2 dba 3 ·CHCl 3 and 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phospha-adamantane allows for Suzuki coupling aryl halides with an array of boronic acids on a solid-phase platform. The reactions can be carried out at room temperature with low palladium loadings in high yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d47f34516d5ef4854a0efd593ab2d947 https://doi.org/10.1016/j.tetlet.2004.05.110 Zobrazit plný text záznamu Full Text from ScienceDirect