Risk factors for hospitalization and severe outcomes of 2009 pandemic H1N1 influenza in Quebec, Canada
| Autor: | Marc Dionne, Jesse Papenburg, Rodica Gilca, Danuta M. Skowronski, Élise Fortin, Guy Boivin, Nicole Boulianne, Gaston De Serres, Monique Douville-Fradet, Najwa Ouhoummane |
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| Rok vydání: | 2011 |
| Předmět: |
Pulmonary and Respiratory Medicine
Pediatrics medicine.medical_specialty Pregnancy Epidemiology business.industry Public Health Environmental and Occupational Health Case-control study medicine.disease Logistic regression medicine.disease_cause Intensive care unit law.invention Infectious Diseases law Pandemic medicine Influenza A virus Young adult business Asthma |
| Zdroj: | Influenza and Other Respiratory Viruses. 5:247-255 |
| ISSN: | 1750-2640 |
| Popis: | Please cite this paper as: Gilca et al. (2011) Risk Factors for Hospitalization and Severe Outcomes of 2009 Pandemic H1N1 Influenza in Quebec, Canada. Influenza and Other Respiratory Viruses 5(4), 247–255 Background/ Objective This case–control study was carried out to estimate risk factors associated with hospitalizations and severe outcomes [intensive care unit (ICU) admission or death] among patients with illness because of laboratory-confirmed 2009 pandemic A/H1N1 virus (pH1N1) during the first wave of pH1N1 activity in the province of Quebec, Canada. Patients/ Methods We collected epidemiologic information by phone using a standardized questionnaire from patients with laboratory-confirmed pH1N1 illness during the first spring/summer pandemic wave in Quebec, Canada. Risk factors associated with hospitalization were assessed by comparing hospitalized to community cases and for ICU admission or death through comparison with hospitalized cases. Results Cases (321 hospitalized patients including 47 ICU admissions and 15 deaths) were compared to controls (395 non-hospitalized patients) by using multivariable logistic regression adjusted for gender, age, education, being a health care worker, smoking, seasonal influenza vaccination, delay to consultation, antiviral use before admission, pregnancy, underlying medical conditions, and obesity. Age |
| Databáze: | OpenAIRE |
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