The mode of the laxative action of Phenolphthalein

Autor:	Philip Blick, J. B. Berardi, Oskar Wozasek
Rok vydání:	1942
Předmět:	medicine.medical_specialty medicine.medical_treatment Gastroenterology Laxative Cathartic General Medicine Pituitrin Phenolphthalein chemistry.chemical_compound Atropine Endocrinology chemistry Internal medicine medicine medicine.drug
Zdroj:	American Journal of Digestive Diseases. 9:292-297
ISSN:	0002-9211
DOI:	10.1007/bf02997911
Popis:	1. Phenolphthalein is not an intestinal irritant as judged by the standards we have given. 2. That phenolphthalein acts directly on the muscle supported by the following facts: (a) Atropine which paralyzes the motor nerves of the intestine does not stop the cathartic action of phenolphthalein. (b) Phenolphthalein does not affect parasympa thetic nerves as judged by its effect of these nerves on the heart. (c) Drugs like eserine which stimulate the intestine through the nerves, also effect the vagus to the heart in a similar manner. 3. Barium or pituitrin, which act on musculature applied locally, effect the intestine in a manner similar to, but more markedly than phenolphthalein.
Databáze:	OpenAIRE
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