The fully synthetic, bio-coated MIRO® CORNEA UR keratoprosthesis: development, preclinical testing, and first clinical results

Autor:	Wolfgang G. K. Müller-Lierheim, Gernot I. W. Duncker, Joachim Storsberg
Rok vydání:	2014
Předmět:	Intraocular pressure medicine.medical_specialty Materials science genetic structures Keratoprosthesis Genetically engineered Glaucoma medicine.disease eye diseases Ophthalmology Ocular tissue medicine.anatomical_structure Preclinical testing Cornea medicine sense organs Acrylic polymer
Zdroj:	Spektrum der Augenheilkunde. 28:250-260
ISSN:	1613-7523 0930-4282
DOI:	10.1007/s00717-014-0243-4
Popis:	Background The MIRO® CORNEA UR is a new keratoprosthesis made of a single piece of flexible, hydrophobic acrylic polymer. The geometry is based on the original Cardona design, allowing epicorneal as well as intrastromal implantation. The haptic is coated with genetically engineered fibronectin, supporting the adherence of surrounding tissue. The flexibility of the haptic minimizes shear stress between keratoprosthesis and ocular tissue, and supports intraocular pressure monitoring in patients with a high incidence of glaucoma.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d45c705bb94da9cdc4c9e2ef8fdb4764 https://doi.org/10.1007/s00717-014-0243-4 Zobrazit plný text záznamu Full text from SpringerLink