Characterization of Maternal Isoagglutinins in ABO Hemolytic Disease of the Newborn

Autor: H. Hugh Fudenberg, Arlene Nuckton, Susie W. Fong
Rok vydání: 1966
Předmět:
Zdroj: Blood. 27:17-37
ISSN: 1528-0020
0006-4971
DOI: 10.1182/blood.v27.1.17.17
Popis: Sera of group O mothers of infants with and without ABO hemolytic disease of the newborn were fractionated by diethylaminoethyl-cellulose chromatography and density gradient ultracentrifugation. Whole sera and serum fractions were evaluated for activity by various test systems currently used for the antenatal prediction of ABO hemolytic disease of the newborn. The results of these studies did not show any single serologic property that would unequivocally diflerentiate between the isoantibodies of mothers of affected infants and mothers of normal infants of incompatible blood group.
Databáze: OpenAIRE