Transformations of N-arylpropiolamides to indoline-2,3-diones and acids via C≡C triple bond oxidative cleavage and C(sp2)–H functionalization

Autor:	Jin-Heng Li, Yang Li, Ming-Bo Zhou, Xuan-Hui Ouyang
Rok vydání:	2019
Předmět:	010405 organic chemistry Stereochemistry General Chemistry 010402 general chemistry Triple bond Cleavage (embryo) 01 natural sciences 0104 chemical sciences Catalysis chemistry.chemical_compound chemistry Functional group Indoline Surface modification Oxidative cleavage
Zdroj:	Science China Chemistry. 63:222-227
ISSN:	1869-1870 1674-7291
DOI:	10.1007/s11426-019-9633-x
Popis:	A new palladium-catalyzed oxidative conversion of N-arylpropiolamides and H2O to various indoline-2,3-diones and acids through the C≡C triple bond cleavage and C(sp2)–H functionalization is described, which is promoted by a cooperative action of catalytic CuBr2, 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) and O2. The method provides a practical tool for transformations of alkynes by means of a C–H functionalization strategy, which enables the formation of one C–C bond and multiple C–O bonds in a single reaction with high substrates compatibility and excellent functional group tolerance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d44440cd0f59eff87c1698a480aef49a https://doi.org/10.1007/s11426-019-9633-x Zobrazit plný text záznamu Full text from SpringerLink