Biomolecule-less sensors for biomolecules based on templated xerogel platforms

Autor: Zunyu Tao, Alexander N. Cartwright, Frank V. Bright, William G. Holthoff, Albert H. Titus, Ellen L. Shughart, Elizabeth C. Tehan, Rachel M. Bukowski, Ying Tang
Rok vydání: 2005
Předmět:
Zdroj: SPIE Proceedings.
ISSN: 0277-786X
DOI: 10.1117/12.629169
Popis: We report on a new strategy for producing self-contained sensor elements for protein detection. The method exploits molecular imprinting, sol-gel-derived xerogels, and selective installation of the fluorescent reporter molecule within the template site. There are no biological reagents used. We term these new xerogel-based sensor elements as Protein Imprinted Xerogels with Integrated Emission Sites (PIXIES). The analytical figures of merit are described.
Databáze: OpenAIRE