Popis: |
The last two decades have seen the advancement in tissue engineering strategies to provide viable alternatives to native tissues, implants, and prostheses. Progress made in biomaterials development assisted with macro-, micro-, and nanotechnologies contributed to mimic the native tissue and its microenvironment for in situ regeneration and further its complete replacement with functional tissues. A key component of this strategy i.e., biomaterials development, requires a range of properties to support regeneration of specific tissues which is mostly unachievable with a sole component and thus needs to be bio-composite of two or more components in specific ratio, form, and distribution. This chapter is dedicated to bio-composites development for tissue engineering applications and will be focusing on the properties required and strategies employed for the development of different types of bio-composites for hard and soft tissue regeneration. The modulation of material properties by compositing with different biomaterials and approaches affecting its functionality and efficiency for tissue regeneration is discussed. This chapter is also reporting the recent advancements as has happened in the terrain of bio-composites for tissue regeneration and the challenges encountered to achieve the benchmark success. |