Rutin nanosuspension for potential management of osteoporosis: effect of particle size reduction on oral bioavailability, in vitro and in vivo activity

Autor:	Sonia Gera, Jitendra Wankar, Venkatesh Pooladanda, Sunitha Sampathi, Sujatha Dodoala, Chandraiah Godugu, Veerabhadra Swamy Challa
Rok vydání:	2020
Předmět:	Drug Antioxidant medicine.medical_treatment media_common.quotation_subject Osteoporosis Pharmaceutical Science 02 engineering and technology General Medicine Pharmacology 021001 nanoscience & nanotechnology medicine.disease 030226 pharmacology & pharmacy In vitro Bioavailability 03 medical and health sciences Rutin chemistry.chemical_compound 0302 clinical medicine chemistry In vivo medicine Clinical significance 0210 nano-technology media_common
Zdroj:	Pharmaceutical Development and Technology. 25:971-988
ISSN:	1097-9867 1083-7450
Popis:	Clinical significance of Rutin (RUT) is limited by poor dissolution rate and low oral bioavailability. The study was designed to improve the physicochemical and therapeutic potential of the drug by...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d41cfb662b4a83e7bab80cf4ca0869cc https://doi.org/10.1080/10837450.2020.1765378 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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