Autor: |
Susumo Katoh, J. Ernest Villafranca, Cristina T. Lewis, Michael Imbacuan, Richard E. Showalter, Babine Robert E, Littlefield Ethel S, Judy V. French, Hans E. Parge, Ted M. Bleckman, John H. Tatlock, L. A. K. Pelletier |
Rok vydání: |
1996 |
Předmět: |
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Zdroj: |
Bioorganic & Medicinal Chemistry Letters. 6:385-390 |
ISSN: |
0960-894X |
DOI: |
10.1016/0960-894x(96)00032-7 |
Popis: |
The design, synthesis, and structure activity relationships of a series of novel macrocyclic FKBP-12 ligands 1 are reported. The crystal structure of the complex between 7 and human FKBP-12 is reported and some SAR results are discussed based on this complex. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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