Human Intestinal Disaccharidase Activity
Autor: | Anthony Walker, G. Victor Rohrer, Jack D. Welsh, June C. May, Robert Drewry |
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Rok vydání: | 1966 |
Předmět: |
Lactose intolerance
medicine.medical_specialty Malabsorption business.industry medicine.medical_treatment Lactase medicine.disease Gastroenterology Small intestine Disaccharidase Enteritis Diarrhea medicine.anatomical_structure Internal medicine Internal Medicine medicine Alkaline phosphatase medicine.symptom business |
Zdroj: | Archives of Internal Medicine. 117:495 |
ISSN: | 0003-9926 |
Popis: | PRIMARY and secondary intestinal disaccharidase deficiencies were first described in children1; however, such enzyme deficiencies also occur in adults.2,3We have previously reported4the results of oral lactose tolerance tests in a group of healthy individuals, our ranges of normal intestinal disaccharidase and alkaline phosphatase activity, and the spatial location of these enzymes in the proximal small intestine. The present study concerns disaccharide tolerance tests and assays of intestinal disaccharidase and alkaline phosphatase activity in patients with various gastrointestinal diseases. Material and Methods Patients. —The 20 Caucasian patients in this study ranged in age from 27 to 79 years; two had an isolated lactase deficiency, four had undergone gastric surgery for benign peptic-ulcer disease, one had sucrose-isomaltose malabsorption, two had diarrhea with streatorrhea, one had regional enteritis, and ten had adult celiac disease. Methods. —The methods used for the tolerance tests, D-xylose excretion test, and stool fat |
Databáze: | OpenAIRE |
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