THE INFLUENCE OF THE PITUITARY GROWTH HORMONE ON MUSCLE GLYCOGEN IN ADRENALECTOMIZED AND HYPOPHYSECTOMIZEDADRENALECTOMIZED RATS1

Autor:	Roger H. Bowman
Rok vydání:	1957
Předmět:	Pituitary growth hormone medicine.medical_specialty Pituitary gland Hormone activity Glycogen Somatotropic cell Biology Growth hormone chemistry.chemical_compound Endocrinology medicine.anatomical_structure chemistry Internal medicine medicine Hormone Endocrine gland
Zdroj:	Endocrinology. 61:500-505
ISSN:	1945-7170 0013-7227
Popis:	NORMAL levels of muscle glycogen can not be maintained in the hypophysectomized animal during a fast. The administration of pituitary growth hormone lessens the glycogen depletion, and this hormonal activity is spoken of as the glycostatic effect (1,2). Illingworth and Russell (3) investigated the glycogen response to purified growth hormone in animals with pituitaries intact. They found that in the normal animal glycogen levels were elevated significantly six hours after injection, whereas the hormone was relatively ineffective in acutely treated adrenalectomized rats. Recently, however, even in the normal animal muscle glycogen has been reported to be unaffected by growth hormone in short term experiments (4, 5). The object of the present experiments was to investigate the effects of purified growth hormone on muscle glycogen as affected by the pituitary and adrenal glands, as well as by the duration of hormone treatment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d3cfc74e8ce6034522734a67385342c6 https://doi.org/10.1210/endo-61-5-500 Zobrazit plný text záznamu