| Autor: | Ta C. Wu, Win L. Chiou, Sang M. Chung |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Pharmacology
biology Ratón Metabolite Organic Chemistry Pharmaceutical Science chemical and pharmacologic phenomena Tacrolimus Bioavailability chemistry.chemical_compound surgical procedures operative chemistry Pharmacokinetics Oral administration Knockout mouse biology.protein Molecular Medicine Pharmacology (medical) Biotechnology P-glycoprotein |
| Zdroj: | Pharmaceutical Research. 17:205-208 |
| ISSN: | 0724-8741 |
| DOI: | 10.1023/a:1007573531947 |
| Popis: | Purpose. To study the contribution of P-glycoprotein (P-gp) to the oralabsorption of a substrate, tacrolimus, by comparing the extent and rateof bioavailability in normal and mdr1a knockout mice. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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