Phosphorescence Kinetics of Singlet Oxygen in HeLa Cells Suspension
| Autor: | V. P. Belik, Elena S. Kornilova, T. N. Belyaeva, D. M. Beltukova, Oleg S. Vasyutinskii, Irina V. Semenova, I. M. Gadzhiev, I. K. Litvinov |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
inorganic chemicals
010302 applied physics Physics and Astronomy (miscellaneous) biology Chemistry Singlet oxygen medicine.medical_treatment Kinetics Photodynamic therapy 02 engineering and technology 021001 nanoscience & nanotechnology Photochemistry biology.organism_classification 01 natural sciences HeLa chemistry.chemical_compound biological sciences 0103 physical sciences polycyclic compounds medicine Photosensitizer Triplet state 0210 nano-technology Suspension (vehicle) Phosphorescence |
| Zdroj: | Technical Physics Letters. 45:936-939 |
| ISSN: | 1090-6533 1063-7850 |
| DOI: | 10.1134/s1063785019090165 |
| Popis: | The kinetics of singlet oxygen phosphorescence in HeLa cells suspended in phosphate buffered saline (PBS) being generated under photosensitized excitation with Radachlorin photosensitizer has been observed and studied. The characteristic time of singlet oxygen generation and its lifetime in HeLa cells have been determined. The experimental data analysis demonstrated that the singlet oxygen lifetime in cells decreases as compared to that in Radachlorin solutions in PBS and in water, while the photosensitizer triplet state lifetime increases. |
| Databáze: | OpenAIRE |
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