Fallopian tube cytology: A histocorrelative study of 150 washings

Autor: Nicholas J. Mulvany, Maryann Arnstein, Andrew G. Östör
Rok vydání: 1997
Předmět:
Zdroj: Diagnostic Cytopathology. 16:483-488
ISSN: 1097-0339
8755-1039
DOI: 10.1002/(sici)1097-0339(199706)16:6<483::aid-dc3>3.0.co;2-b
Popis: The aim of the study was to assess the relationship between fallopian tube lavage cytology and recognized microscopic prognostic features in cancer of the uterine corpus. Tubal (TW) and peritoneal washing cytology (PW), endometrial tumor grade, and tumor involvement of the cervix, myometrium, myometrial vessels, and peritoneum were assessed in 150 patients. Endometrioid adenocarcinoma grade 1 was considered a low-grade tumor, while endometrioid carcinoma grades 2/3, serous/clear cell carcinoma, carcinosarcoma, and high-grade stromal sarcoma were considered high grade. The overall concordance rate for paired TWs and PWs was 72% (108/150). Forward stepwise logistic regression analysis of the 150 tumors revealed that only PWs and cervical involvement were independently predictive of TWs. No relationship was evident between TWs and depth of myometrial invasion, myometrial vascular involvement, or peritoneal metastases. It is concluded that retrograde transtubal spread by malignant endometrial cells occurs independently of myometrial histoprognostic features. TWs provide supporting evidence for diagnostically difficult PWs, and malignant TWs may be detected in the presence of minimally invasive serous/clear cell carcinoma and carcinosarcoma of the endometrium. Diagn. Cytopathol. 16:483–488, 1997. © 1997 Wiley-Liss, Inc.
Databáze: OpenAIRE
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