Synthesis and the crystal and molecular structures of 4-(piperidyl-1)-2-phenylpyrido[2,3-a]anthraquinone-7,12 Mono- and dibromohydrates (HL)Br · 3H2O and (H2 L)Br2 · 3H2O

Autor:	B. E. Zaĭtsev, Olga V. Kovalchukova, M. A. Ryabov, Adam I. Stash, Vitaly K. Belsky, Svetlana Strashnova
Rok vydání:	2009
Předmět:	Stereochemistry Protonation General Chemistry Crystal structure Condensed Matter Physics Medicinal chemistry Anthraquinone Crystal chemistry.chemical_compound chemistry X-ray crystallography Pyridine Molecule General Materials Science Piperidine
Zdroj:	Crystallography Reports. 54:68-73
ISSN:	1562-689X 1063-7745
DOI:	10.1134/s106377450901012x
Popis:	4-(Piperidyl-1)-2-phenylpyrido[2,3-a]anthraquinone-7,12 monobromohydrate (HL)Br · 3H2O (I) and 4-(piperidyl-1)-2-phenylpyrido[2,3-a]anthraquinone-7,12 dibromohydrate (H2L)Br2 · 3H2O (II) are isolated in the crystalline state. The crystal structures of compounds I and II are determined using X-ray diffraction. It is established that the protonation of 4-(piperidyl-1)-2-phenylpyrido[2,3-a]anthraquinone-7,12 proceeds primarily through the pyridine atom at pH 2–3. The attachment of the second proton occurs through the piperidine nitrogen atom at pH ∼ 1.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d38a1861d9eb0a95537d2625d8a42a4f https://doi.org/10.1134/s106377450901012x Zobrazit plný text záznamu Plný text ve formátu PDF