| Popis: |
Purpose: Numerous studies suggesting that stable pneumothorax can be treated by observation alone. The present study aimed to compare observation alone VS interventional procedure in treating hemodynamically stable adult patient with pneumothorax for outcomes of clinical efficacy, tolerability, and safety. Methods: In this systematic review and meta-analysis, we searched PubMed and Google Scholar, from inception until June 24, 2020 for RCTs comparing observational therapy with conventional therapy in management of pneumothorax in adult. We excluded tension pneumothorax and paediatric aged group. Results: Three RCTs enrolled 446 patients. Compared to chest tube, observation had almost same failure rate (RR 4.30; 95% CI= 0.23-81.82, p= 0.33) and same mortality (RR 1.01; 95% CI= 0.31-3.33, p= 0.98). Risks of complications; tension pneumothorax and empyema were similar between chest tube and observation (RR 3.15; 95% CI= 0.67-14.87, p= 0.15) and (RR 1.55; 95% CI= 0.21-11.56, p= 0.67) respectively. There was no statistically significant difference in hospital days between chest tube and observation. Conclusions: In stable adult patients with pneumothorax, the observation has same efficacy and safety in treating pneumothorax compare to chest tube. Funding: None to declare. Declaration of Interest: None to declare. |
