Electrochemical behavior and determination of baicalin on a glassy carbon electrode modified with molybdenum disulfide nano-sheets
| Autor: | FengFu Fu, Tong-Ying Wang, Hongyan Zhang, Yu-yan Yu, Yali Qiu |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Detection limit
Supporting electrolyte General Chemical Engineering 010401 analytical chemistry Inorganic chemistry 02 engineering and technology 021001 nanoscience & nanotechnology Electrochemistry 01 natural sciences 0104 chemical sciences Analytical Chemistry chemistry.chemical_compound chemistry Electrode Differential pulse voltammetry Cyclic voltammetry 0210 nano-technology Molybdenum disulfide Baicalin |
| Zdroj: | Journal of Electroanalytical Chemistry. 775:286-291 |
| ISSN: | 1572-6657 |
| DOI: | 10.1016/j.jelechem.2016.06.017 |
| Popis: | In this study, a molybdenum disulfide (MoS 2 ) nano-sheets-modified glassy carbon electrode (GCE) was prepared, and the electrochemical behavior of baicalin on the proposed electrode was investigated by cyclic voltammetry (CV) in PBS buffer solution (pH 7.0). The experimental results showed that baicalin exhibits enhanced voltammetric response on the MoS 2 -modified GCE. Based on the enhanced voltammetric response of baicalin on the MoS 2 -modified GCE, a sensitive and selective electrochemical method for the determination of baicalin was developed by using differential pulse voltammetry (DPV). Various experimental parameters including the pH of supporting electrolyte, amount of MoS 2 nano-sheets and accumulation time were optimized. Under the optimized conditions, the oxidation peak current was linearly proportional to the baicalin concentrations in the range of 1.25 × 10 − 7 M–1.25 × 10 − 5 M, and the detection limit (S/N = 3) was calculated to be 5.0 × 10 − 8 M. The developed method was successfully used to detect baicalin in pharmaceutical samples with a recovery of 97–109% and a relative standard deviation (RSD, n = 6) |
| Databáze: | OpenAIRE |
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