ChemInform Abstract: Phosphinoaryl- and Phosphinoalkyloxazolines as New Chiral Ligands for Enantioselective Catalysis: Very High Enantioselectivity in Palladium- Catalyzed Allylic Substitutions

Autor:	Günter Helmchen, Jürgen Sprinz
Rok vydání:	2010
Předmět:	Substitution reaction chemistry.chemical_compound Allylic rearrangement chemistry Enantioselective synthesis chemistry.chemical_element Chelation General Medicine Combinatorial chemistry Dimethyl malonate Catalysis Palladium
Zdroj:	ChemInform. 24
ISSN:	0931-7597
Popis:	Chiral phosphinoaryl- and phosphinoalkyloxazolines, a new class of chelate ligands, were prepared via convenient routes. Palladium complexes of the new ligands have proved to be highly effective catalysts for allylic substitution reactions. Enantioselectivity of up to 98.5 % ee in the reaction of dimethyl malonate with 1,3-diphenyl-2-propenyl acetate is the highest so far achieved in this area.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d35dc46563db9288500da3f04b0f91c7 https://doi.org/10.1002/chin.199330067 Zobrazit plný text záznamu Plný text