Remote, 1,5-anti stereoinduction in the boron-mediated aldol reactions of β-oxygenated methyl ketones

Autor:	Ian Paterson, Karl Richard Gibson, Renata M. Oballa
Rok vydání:	1996
Předmět:	Aldol reaction Chemistry Organic Chemistry Drug Discovery chemistry.chemical_element Organic chemistry Stereoselectivity Altohyrtin A Boron Biochemistry Spongistatin 1
Zdroj:	Tetrahedron Letters. 37:8585-8588
ISSN:	0040-4039
DOI:	10.1016/0040-4039(96)01962-4
Popis:	High levels of 1,5-stereoinduction are obtained in the boron-mediated aldol reactions of β-oxygenated methyl ketones 5,7 and 8 with achiral aldehydes. The aldol products undergo stereoselective reductions, providing an efficient method of accessing a wide range of 1,3-polyols.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d3496bee1e4f562cb627c81c64a3b3ba https://doi.org/10.1016/0040-4039(96)01962-4 Zobrazit plný text záznamu Full Text from ScienceDirect