Effects of intraperitoneal lidocaine combined with intravenous or intraperitoneal tenoxicam on pain relief and bowel recovery after laparoscopic cholecystectomy
| Autor: | M. Elhakim, S. Kamel, H. Amine, F. Saad |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
medicine.medical_specialty
Lidocaine business.industry Local anesthetic medicine.drug_class Nausea medicine.medical_treatment Analgesic General Medicine Surgery Route of administration Anesthesiology and Pain Medicine Tenoxicam Anesthesia medicine Cholecystectomy medicine.symptom business Saline medicine.drug |
| Zdroj: | Acta Anaesthesiologica Scandinavica. 44:929-933 |
| ISSN: | 0001-5172 |
| DOI: | 10.1034/j.1399-6576.2000.440806.x |
| Popis: | Background: Previous work has demonstrated that intraperitoneal (i.p.) lidocaine may provide analgesia after laparoscopic cholecystectomy. The aim of this prospective, randomized, double-blind study was to compare pain relief, recovery variables, and side effects after i.p. instillation of lidocaine plus tenoxicam given either i.v. or i.p. after laparoscopic cholecystectomy. Methods: Ninety patients were randomly allocated to one of three groups to receive either 200 ml normal saline i.p. and 2 ml of normal saline i.v. (saline group), 200 ml lidocaine 0.1% i.p. and 2 ml tenoxicam 20 mg i.v. (tenoxicam i.v. group), or 200 ml lidocaine 0.1% with 20 mg tenoxicam i.p. and 2 ml of normal saline i.v. (tenoxicam i.p. group). The i.p. instillation was made under the right diaphragm and on the gall bladder bed. VAS pain scores at rest, on movement and during coughing, were measured 2, 4, 6, 12, and 24 h after operation. The time to first demand of analgesia, total analgesic requirement, recovery variables, and side effects were investigated. Results: In the tenoxicam i.p. group, pain scores were significantly lower both at rest and on movement and analgesic consumption was reduced compared with the saline group (P |
| Databáze: | OpenAIRE |
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