Ovarian Cancer Biomarkers in Proximal Fluids

Autor:	Gabriel D. Dakubo
Rok vydání:	2019
Předmět:	Oncology medicine.medical_specialty Ductal lavage business.industry medicine.disease Molecular biomarkers Breast cancer Nipple Aspirate Fluid Internal medicine medicine skin and connective tissue diseases Ovarian cancer Risk assessment business Breast fluid Breast anatomy
Zdroj:	Cancer Biomarkers in Body Fluids ISBN: 9783030247232
DOI:	10.1007/978-3-030-24725-6_10
Popis:	Key Topics Relate breast cytoarchitecture to its proximal fluid representation of the entire breast. Types and features of proximal breast fluids. Breast cancer (BrCa) risk assessment using biomarkers in proximal fluids. Commercial application of BrCa management using biomarkers in proximal fluids. Key Points Breast anatomy and the sick lobe hypothesis of BrCa suggest biomarkers from some lesions in the breast might not be represented in breast proximal fluids. The intraductal approach with acquisition of breast fluid for risk assessment has been practiced since the early 1940s and is currently useful for risk assessment in women at elevated risk. Nipple aspirate fluid acquisition is more amenable to be deployed for BrCa screening but contains less cells than the minimally invasive ductal lavage approach. Molecular biomarkers in breast proximal fluids should augment cytomorphologic assessment of BrCa risk and early detection.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d2d3d6346f5498cfdd0305e7f6f001ff https://doi.org/10.1007/978-3-030-24725-6_10 Zobrazit plný text záznamu