Retinal nerve fibre layer thickness measurements by optical coherence tomography in patients with sleep apnoea syndrome

Autor: Orna Geyer, Oded Sagiv, Idit Lavi, Ron Peled, Gila Buckman, Julia Wolfson, Tagil Fishelson-Arev, Eitan Segev, Nurit Mathalone
Rok vydání: 2013
Předmět:
Zdroj: Clinical & Experimental Ophthalmology. 42:132-138
ISSN: 1442-6404
DOI: 10.1111/ceo.12145
Popis: Background The study aims to investigate whether retinal nerve fibre layer (RNFL) abnormalities can be detected in patients with obstructive sleep apnoea/hypopnoea syndrome with normally appearing optic disc. Design This is an observational case-control study. Participants One hundred and eight consecutive patients with moderate or severe obstructive sleep apnoea/hypopnoea syndrome (OSAHS) as determined by overnight polysomnography and normal looking discs and 108 age-matched healthy controls were included in the study. Methods All patients underwent RNFL examinations by optical coherence tomography using fast retinal nerve fibre layer thickness scan. Main Outcome Measures The main outcome measure was RNFL thickness. Results Multivariate regression analysis results showed that the RNFL was thinner for a patient with OSAHS than that of a normal control in the average by 4.20 μm (P
Databáze: OpenAIRE