Zeolite catalysed synthesis of coumarin derivatives

Autor:	A. J. Hoefnagel, Herman van Bekkum, E.A. Gunnewegh
Rok vydání:	1995
Předmět:	chemistry.chemical_classification Process Chemistry and Technology Carboxylic acid Substituent Alkylation Heterogeneous catalysis Toluene Catalysis chemistry.chemical_compound chemistry Organic chemistry Physical and Theoretical Chemistry Aliphatic compound Acrylic acid
Zdroj:	Journal of Molecular Catalysis A: Chemical. 100:87-92
ISSN:	1381-1169
DOI:	10.1016/1381-1169(95)00156-5
Popis:	The direct synthesis of coumarin derivatives from m-substituted phenols and α,β-unsaturated carboxylic acids catalysed by solid-acid catalysts, such as zeolite H-Beta or Amberlyst-15, in toluene as solvent was studied. The conversion involves esterification followed by alkylation (ring closure). Ring closure of the ester is promoted both by an appropriate substituent on the aromatic ring and by Michael activation of the β-carbon of the ester. These influences were studied by variation of the reactants. 7-Hydroxy-3,4-dihydrocoumarin is formed in high yield when resorcinol and propenoic acid are used as reactants.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d2ae9ea451d45d47d12a8cf80b6dfd06 https://doi.org/10.1016/1381-1169(95)00156-5 Zobrazit plný text záznamu Full Text from ScienceDirect