Newly diagnosed enhancing lesions: Steroid initiation may impede diagnosis of lymphoma involving the central nervous system
| Autor: | Qinwen Mao, Nabeel R. Yaseen, Liron Barnea Slonim, Kwok-Ling Kam, Daniel J. Brat, Rimas V. Lukas, Sarah M. Brooker, Adam M. Sonabend |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
business.industry Central nervous system General Medicine Newly diagnosed Disease medicine.disease Delayed diagnosis Lymphoma 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Neurology Primary CNS Lymphoma 030220 oncology & carcinogenesis Physiology (medical) medicine Surgery In patient Involution (medicine) Neurology (clinical) Intensive care medicine business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Clinical Neuroscience. 81:61-64 |
| ISSN: | 0967-5868 |
| DOI: | 10.1016/j.jocn.2020.09.014 |
| Popis: | Establishing the pathologic diagnosis of central nervous system (CNS) lymphoma can be challenging, yet management of this potentially curable disease depends heavily on it. One avoidable impediment to obtaining an accurate and timely diagnosis is the pre-operative administration of steroids, which causes tumor involution and prevents appropriate sampling of viable tissue. We discuss a case of primary CNS lymphoma that highlights the evolution of the disease and the attempts to establish a diagnosis in the setting of prior administration of corticosteroids. Familiarity with these clinical scenarios will help others avoid delays in patient care that results from delayed diagnosis. |
| Databáze: | OpenAIRE |
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