Discrepant HPV/cytology cotesting results: Are there differences between cytology-negative versus HPV-negative cervical intraepithelial neoplasia?
| Autor: | Isam-Eldin Eltoum, Antoinette D. Davis, Jessica Tracht, Danielle Fasciano |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Cancer Research medicine.medical_specialty Cervical intraepithelial neoplasia Malignancy 03 medical and health sciences 0302 clinical medicine HPV Negative Cytology mental disorders Biopsy medicine Sampling (medicine) medicine.diagnostic_test business.industry virus diseases Cancer medicine.disease Dermatology female genital diseases and pregnancy complications 030104 developmental biology Oncology 030220 oncology & carcinogenesis business Ascus psychological phenomena and processes |
| Zdroj: | Cancer Cytopathology. 125:795-805 |
| ISSN: | 1934-662X |
| Popis: | BACKGROUND The objective of this study was to compare cervical high-grade squamous intraepithelial lesions subcategorized as cervical intraepithelial neoplasia-3 (CIN-3)–positive after a negative cytology result but positive for high-risk human papillomavirus (HR-HPV) testing to those with a negative HR-HPV test but positive cytology (atypical squamous cells of undetermined significance [ASCUS]-positive/HPV-negative) and to assess reasons for discrepancies. METHODS The authors retrospectively analyzed women who underwent screening with cytology and HPV testing from 2010 through 2013. After a review of surgical specimens and cytology, discrepancies were classified as sampling or interpretation error. Clinical and pathologic findings were compared. RESULTS In total, 15,173 women (age range, 25-95 years; 7.1% were aged |
| Databáze: | OpenAIRE |
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