Immunointervention in Type 1 (Insulin-Dependent) Mellitus Diabetes

Autor:	Guido Somers, Bart Keymeulen
Rok vydání:	1993
Předmět:	Type 1 diabetes Nicotinamide business.industry Azathioprine General Medicine Disease medicine.disease medicine.disease_cause Autoimmunity Clinical trial chemistry.chemical_compound chemistry Cyclosporin a Insulin dependent diabetes Immunology medicine business medicine.drug
Zdroj:	Acta Clinica Belgica. 48:86-95
ISSN:	2295-3337 1784-3286
DOI:	10.1080/17843286.1993.11718292
Popis:	The hitherto identified hallmarks of the autoimmune aspects in Type 1 diabetes are reviewed. Their implication in the disclosure of the pre-clinical phase of the disease is put forward. The possible delineation of this pre-diabetic phase can lead to an early immunotherapeutic approach. The effect of immunomodulation by agents such as azathioprine, cyclosporin A and nicotinamide in newly diagnosed diabetes and the use of some of these drugs in clinical trials on pre-diabetic individuals are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d2920c2d9e3d769bb822bd1b630a24c0 https://doi.org/10.1080/17843286.1993.11718292 Zobrazit plný text záznamu