Adrenalectomy in the Shay Rat
| Autor: | Helen H. Ramsburg, Robert J. Madden |
|---|---|
| Rok vydání: | 1951 |
| Předmět: |
medicine.medical_specialty
Hepatology business.industry Adrenalectomy medicine.medical_treatment digestive oral and skin physiology Gastroenterology medicine.disease digestive system diseases Gastric secretion Endocrinology Internal medicine Peptic ulcer medicine Normal rate Cortisone business Saline medicine.drug |
| Zdroj: | Gastroenterology. 18:128-134 |
| ISSN: | 0016-5085 |
| DOI: | 10.1016/s0016-5085(51)80042-8 |
| Popis: | Summary 1.ACTH, cortisone (CA) or desoxycorticosterone (DCA) had no beneficial effect upon the extent or severity of the ulcers seen in the forestomach of the pylorus-ligated rat. 2.DCA and, to a lesser extent, CA produced small increases in gastric secretion in pylorus-ligated rats with intact adrenals. 3.Adrenalectomy profoundly lowered the volume of gastric secretion and almost completely prevented ulceration of the forestomach in pylorus-ligated rats. 4.The administration of normal saline, normal glucose solution, ACE, CA, and DCA partially restored the volume of gastric juice in adrenalectomized pylorus-ligated rats. 5.Partial restoration, with adequate therapy, of the normal rate of gastric secretion after adrenalectomy had as its corollary that increasing amounts of forestomach ulcerations were present. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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