Antinociceptive, anti-inflammatory and antipyretic effects of ethanolic root bark extract of Icacina senegalensis in rodents
| Autor: | Daniel Ogbonna John Aja, Godknows K Ogbuji, Juliet Ifeoma Obiajunwa-Otteh, Esien David-Oku, E. E. Edet, Godwin Christian Akuodor |
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| Rok vydání: | 2016 |
| Předmět: |
Traditional medicine
Chemistry medicine.drug_class 030231 tropical medicine Egg albumin Medicine (miscellaneous) complex mixtures Anti-inflammatory 03 medical and health sciences 0302 clinical medicine Nociception Icacina senegalensis medicine Pharmacology (medical) Antipyretic General Pharmacology Toxicology and Pharmaceutics 030223 otorhinolaryngology Abdominal constriction medicine.drug |
| Zdroj: | Journal of Applied Pharmaceutical Science. :104-108 |
| ISSN: | 2231-3354 |
| DOI: | 10.7324/japs.2016.60215 |
| Popis: | To investigate the ethanolic root bark extract of Icacina senegalensis for antinociceptive, anti-inflammatory and antipyretic activities in rats and mice. Acetic acid-induced abdominal constriction and tail immersion tests were used to evaluate the antinociceptive activity of the extract. Egg albumin and carrageenan-induced paw oedema were used to study the anti-inflammatory activity, whereas the anti-pyretic studies were evaluated on yeast and amphetamine-induced pyrexia. The root bark extract (50, 100 and 200 mg/kg) significantly (P |
| Databáze: | OpenAIRE |
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