Efectividad de la palifermina en la prevención de la mucositis oral en pacientes oncohematológicos

Autor:	R. Ferriols Lisart, D. Ayago Flores
Rok vydání:	2010
Předmět:	Pharmacology medicine.medical_specialty business.industry Incidence (epidemiology) Retrospective cohort study Neutropenia medicine.disease Gastroenterology Sepsis Parenteral nutrition Palifermin Internal medicine Mucositis Medicine business Febrile neutropenia medicine.drug
Zdroj:	Farmacia Hospitalaria. 34:163-169
ISSN:	1130-6343
DOI:	10.1016/j.farma.2009.12.005
Popis:	Objective: To assess the effectiveness of palifermin for the prevention of oral mucositis in patients with haematological cancers. Methods: Retrospective observational study of cohorts of patients with haematological cancer undergoing cytotoxic therapy causing hematopoietic ablation. The main variable assessed was the duration of the oral mucositis. Secondary variables assessed were incidence of mucositis, febrile or septic neutropenia and the administration of opioids and parenteral nutrition. Results: We included 36 patients in this study, 11 in the group that received palifermin and 25 in the control group. The duration of oral mucositis was 4.6 + 3.1 days (median: 5 days) in the patients treated with palifermin in comparison with 7.4 + 4.0 days (median: 6 days) in patients treated with conventional prophylactic therapy (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d26a9cb97077da030164c02d281fba94 https://doi.org/10.1016/j.farma.2009.12.005 Zobrazit plný text záznamu